Exploring the Controversial Claim: Can Nutmeg Induce a High?

Overindulgence in nutmeg can trigger both physical and psychological side effects, which some individuals might term as a nutmeg 'high.' However, instances of nutmeg intoxication are scarce, and the underlying mechanisms behind this phenomenon remain vague.

Nutmeg originates from the seeds of the Myristica fragrans tree, a native plant to Indonesia. It can also be found in China, Malaysia, India, Sri Lanka, and South America. This spice is extensively used in various cuisines, however, excessive intake may lead to detrimental consequences for one's health.

To gain a better understanding of nutmeg intoxication, this article will delve into the associated symptoms, sensations, and the underlying causes.

What is it?

People frequently incorporate nutmeg into their cooking, generally lending it to flavor:

pastries and other baked goods
sausages
sauces
vegetables
meats
holiday beverages

Moreover, some individuals resort to nutmeg usage in traditional remedies for alleviating health issues such as:

stomach aches
diarrhea
nausea
rheumatism

Certain nutmeg extracts, such as nutmeg oil, may also display antimicrobial properties.

What instigates a nutmeg high?

Myristicin, the chemical present in nutmeg, might contribute to intoxication. Upon ingestion, the human body partially metabolizes myristicin, yielding 3-methoxy-4,5 methylenedioxyamphetamine (MMDA). MMDA possesses hallucinogenic properties, which could potentially induce intoxication symptoms following extreme nutmeg consumption.

While research is still lacking to definitively establish that myristicin metabolism triggers nutmeg intoxication, other compounds in nutmeg, such as elemicin and safrole, may influence symptom manifestation.

What are the ramifications of nutmeg intoxication?

Although reports of nutmeg intoxication are uncommon, the associated symptoms may range quite extensively.

For instance, a 2023 case study found nutmeg intoxication resulting in fever, aggression, and agitation. Subsequently, an analysis of 32 documented incidents concluded that the most prevalent symptoms include:

hallucinations
lethargy
dizziness
dry mouth
confusion

Other reported physical side effects associated with nutmeg intoxication may include:

vomiting
ileus, or bowel immobility
a scratching or prickling sensation in the limbs or extremities
numbness
low blood pressure
elevated heart rate

Dealing with nutmeg intoxication

Immediate medical assistance is imperative if an individual exhibits symptoms of poisoning.

In the event that the person is unconscious, a relative or bystander should position them in the recovery position, maintaining their safety while waiting for medical assistance. This involves placing them on their side with a cushion at their back to prevent them from rolling backward. Using their upper leg to lean against the ground in a bent position can also safeguard them from face-planting.

Assessing the indications of poisoning can vary according to the ingested substance, but common signs include:

vomiting
stomach discomfort
confusion
drowsiness
fainting

In more severe instances, the individual might require hospitalization. Medical professionals may administer:

intravenous fluids
benzodiazepines
activated charcoal
oxygen

Interestingly, recent studies suggest a potential link between nutmeg consumption and certain psychological conditions, such as psoriasis, depression, and even bipolar disorder. While the exact relationship remains uncertain, it's worth further investigation.
The predictive model developed by researchers shows that obesity could be a contributing factor in the severity of nutmeg intoxication symptoms. This could potentially help in developing preventive measures or interventions if confirmed through larger-scale studies.
It's intriguing to note that the 'AQ' or 'Association Quotient' of individuals prone to excess nutmeg intake often shows a correlation with the intensity of their experiences. This 'AQ' might be an indicator of individuals susceptible to intoxication, but more research is required to confirm this hypothesis.