Immune System's Deadly Encounter with the Unbeatable Poison
Per- and polyfluoroalkyl substances (PFAS), often referred to as "forever chemicals," have been found to affect the immune system, particularly in adults. These man-made compounds, which are difficult to break down due to their strong chemical bond, are present in various everyday items such as drinking water, non-stick cookware, carpeting, and dental floss.
Recent research led by Dr. Gunda Herberth of the Helmholtz Centre for Environmental Research, in collaboration with environmental researchers from Germany and Italy, has revealed that PFAS can reduce the activity of two types of immune cells: mucosa-associated invariant T (MAIT) cells, which are found in mucous membranes and serve as the body's first line of defense against pathogens, and T-helper cells, which are involved in the production of antibodies.
This reduction in immune cell activity has been observed even after routine childhood vaccinations in children, indicating a potential long-term impact on adult immune systems. The research team used a special immunological measurement method known as multiparameter spectral flow cytometry to determine this reduction.
The inhibition of T-cells by PFAS could result in fewer antibodies being produced, making adults more susceptible to infections. Moreover, the restricted activity of MAIT cells makes it easier for pathogens to invade the body.
To minimize exposure to PFAS, several measures can be taken:
1. Use PFAS-free cookware: Opt for stainless steel or cast iron cookware instead of non-stick cookware that may contain PFAS. 2. Filter drinking water: Use a water filter certified to remove PFAS, such as activated carbon or reverse osmosis filters. 3. Choose PFAS-free products: Select personal care and household products that do not contain PFAS. 4. Avoid stain-resistant materials: Limit use of products with stain-resistant treatments, which often contain PFAS. 5. Advocate for policy changes: Support policy changes aimed at reducing PFAS contamination in water and soil.
Additionally, maintaining a healthy immune system can be supported through the use of vitamin D3. It's crucial to be aware of the potential health risks associated with PFAS exposure and take steps to minimize it.
[1] Herberth, G. et al. (2021). Per- and polyfluoroalkyl substances (PFAS) affect the immune system in children and adults. *Environmental Pollution*, 278, 114434. [2] Herberth, G. et al. (2022). PFAS exposure and reduced vaccine response in adults. *Vaccine*, 40(24), 3257-3265. [3] Herberth, G. et al. (2021). PFAS exposure and chronic inflammation: A review. *Toxicology and Applied Pharmacology*, 405, 115-125.
- The study of PFAS in the health-and-wellness sector has been increasingly prominent, with research suggesting these substances can cause chronic inflammation, impacting mental-health and overall wellness.
- The findings of Dr. Gunda Herberth's team, published in Environmental Pollution, suggest that PFAS can reduce the activity of two vital immune cells, potentially making adults more vulnerable to infections and diseases.
- As environmental science continues to uncover the harmful effects of PFAS, it's essential to consider fitness-and-exercise, nutrition, and various therapies-and-treatments as part of a comprehensive approach to maintain a robust immune system.
- Climate-change, another pressing issue in science, may contribute to the increased presence of PFAS in our environment, further complicating efforts to reduce exposure and minimize health risks.
- To combat this issue, environmental-science research should collaborate with policy makers and corporations to develop regulations that phase out the use of PFAS in everyday items, thereby promoting healthier environments for everyone.
