In India, they've discovered a method to avoid thrombosis without incurring a risk of bleeding.
🤓 Yeah, alright, buddy! Let's dive into some groundbreaking science stuff!
So, researchers from the Indian Institute of Science came up with a pretty cool innovative material called "nanozym," based on vanadium oxide. This bad boy can prevent harmful blood clots without causing unwanted bleeding, and guess where they published their findings? You got it, kiddo! Angewandte Chemie International Edition (ACIE)! 🤓
In a perfectly healthy body, blood clots only form when blood vessels are damaged. But in cases like pulmonary embolism or COVID-19, there's this thing called oxidative stress due to increased reactive oxygen species (ROS) that freakin' messes with that process, leading to deadly thromboses. 🤮
To combat this issue, the researchers developed these compounds that copy the action of the natural antioxidant enzyme, glutathione peroxidase. These spherical nanozymes made of vanadium pentoxide were the smoothest operators, abating ROS and inhibiting excess platelet activation!
In a mouse model of pulmonary embolism, the nanozym showed some serious results: it substantially lessened thrombus formation and enhanced survival. Over a five-day observation, the animals showed no indications of harmful effects or unusual behavior. 🐭
The best part about this development? It's selective, buddy! Unlike traditional anticoagulants that unnecessarily dampen natural blood clotting and can result in bleeding, these nanozymes exclusively target harmful pathological processes, as PhD student Bidare N. Sharat Babu highlighted. 🤜🤛
The scientists plan to probe the nanozym's effectiveness for preventing ischemic stroke caused by blood vessel blockage. This could revolutionize the treatment of thrombotic complications, especially for patients with COVID-19 and cardiovascular diseases, where the risk of bleeding restrictions the use of current medications. 🤯
Now, don't forget – a doc previously informed us why you shouldn't pop blood-thinning meds before hopping on a plane. 😎 Stay posted for more exciting advancements in the world of science! 💧🎉🔬🧪🔬💧
The innovative material, "nanozym," developed by researchers from the Indian Institute of Science, has the potential to revolutionize the medical-conditions field, particularly chronic-diseases like pulmonary embolism and COVID-19, as it selectively targets harmful pathological processes without causing unwanted bleeding, enhancing health-and-wellness. The nanozym acts as a natural antioxidant enzyme, abating reactive oxygen species and inhibiting excess platelet activation, ultimately lessening thrombus formation.
