Innovative PEMP Method Revolutionizes Kidney Diagnostics
An innovative method, PEMP, is revolutionizing kidney diagnostics. An interdisciplinary team from University Medicine Greifswald has published a review in Kidney International, detailing how PEMP makes kidney structures visible, measurable, and clinically useful. This breakthrough brings personalized precision medicine a step closer for treating kidney diseases.
The PEMP method, developed at Universitätsmedizin Greifswald, uses 3D super-resolution light microscopy SIM to visualize and quantify delicate podocyte structures in the kidney. It works with common tissue samples taken during biopsies, making it accessible for routine diagnostics, as seen at the University of Texas Medical Branch (UTMB).
A study using 69 kidney biopsies demonstrated the method's ability to distinguish different forms of kidney diseases. The PEMP method offers high speed, accuracy, and standardizability, surpassing classical methods like electron microscopy. The review provides a comprehensive overview of classical analysis methods and shows how PEMP complements and improves them.
The PEMP method, as highlighted in the review, can detect early changes in podocyte structures before typical disease symptoms occur. This innovation brings hope for earlier diagnosis and better treatment of kidney diseases. Despite the promising results, the name of the spin-off company using the PEMP method remains unknown.
