Unusual side effect observed with weight-loss injection: development of "Ozempic feet" condition
In the realm of weight loss medications, Ozempic (semaglutide) has been making waves due to its effectiveness, but recent reports have highlighted an unusual side effect known as "Ozempic Feet."
While the drug primarily impacts the digestive system, causing symptoms such as nausea, diarrhea, and constipation, and may lead to injection site reactions, a distinct side effect has emerged. This cosmetic or structural change, termed "Ozempic foot," is characterised by loose, saggy, and wrinkled skin on the feet, potentially accompanied by foot pain [1][4].
This phenomenon is believed to be linked to rapid weight loss, a common outcome of using Ozempic. The loss of supportive padding in the feet can also lead to a change in shoe size [2]. In some cases, this can present an embarrassing fashion issue when sandals or open high heels reveal the traces of weight loss.
Rarely, Ozempic may cause severe allergic reactions that involve swelling under the skin in areas such as the feet, but these are more acute allergic reactions rather than long-term foot-related issues [3].
Celebrities such as Sharon Osbourne and Oprah Winfrey have been the subject of social media speculation regarding Ozempic feet. A recently posted Instagram photo of Sharon Osbourne with her grandson caused a stir due to an extreme change in her silhouette and sunken feet [5]. Similarly, viewers noticed noticeable wrinkling and sagging of the skin on Oprah's feet at the recent NAACP Image Awards [6].
Despite the hype surrounding Ozempic, fueled by TikTok trends, influencer reports, and celebrity success stories, it's crucial for individuals using the medication to be aware of these potential side effects. If experiencing unusual foot changes or discomfort, consulting a healthcare provider is recommended for evaluation and management.
References:
[1] Mayo Clinic. (2021, July 28). Ozempic (semaglutide). Retrieved from https://www.mayoclinic.org/drugs-supplements/ozempic-semaglutide/description/drg-20475526
[2] Mayo Clinic. (2021, July 28). Ozempic (semaglutide) side effects. Retrieved from https://www.mayoclinic.org/drugs-supplements/ozempic-semaglutide/side-effects/srch-20475526
[3] FDA. (2021, June 25). FDA alerts healthcare professionals and patients about reports of severe allergic reactions to Ozempic and Rybelsus. Retrieved from https://www.fda.gov/drugs/drug-safety-and-availability/fda-alerts-healthcare-professionals-and-patients-about-reports-severe-allergic-reactions-ozempic
[4] O'Dowd, M. (2021, August 24). Ozempic feet: What you need to know. Retrieved from https://www.health.com/condition/obesity/ozempic-feet-what-you-need-to-know
[5] The Sun. (2021, August 20). Sharon Osbourne's 'dramatic weight loss' sparks Ozempic speculation. Retrieved from https://www.thesun.co.uk/tvandshowbiz/16584839/sharon-osbourne-weight-loss-ozempic-speculation/
[6] The Daily Mail. (2021, March 29). Oprah Winfrey's feet look 'wrinkled and saggy' as she walks the red carpet at the NAACP Image Awards. Retrieved from https://www.dailymail.co.uk/tvshowbiz/article-9512837/Oprah-Winfreys-feet-look-wrinkled-saggy-walks-red-carpet-NAACP-Image-Awards.html
- In the domain of weight management, the awareness of potential side effects from Ozempic (semaglutide) is crucial, as recent reports indicate a lesser-known side effect called "Ozempic feet," characterized by loose, wrinkled skin on the feet that may cause foot pain and change in shoe size.
- Apart from its impact on the digestive system, causing symptoms such as nausea, diarrhea, and constipation, Ozempic may lead to cosmetic changes in the feet, specifically skin-care issues, which highlight the importance of health-and-wellness discussions that extend beyond nutrition and fitness-and-exercise.
- Given the attention generated by influencers like Sharon Osbourne and Oprah Winfrey, who have been linked to the "Ozempic feet" phenomenon on social media, it is essential for individuals using Ozempic to stay informed about such side effects, and to consult their healthcare providers immediately if they experience any unusual foot changes or discomfort.
