Vitamin B17, or Amygdalin, Presented as Ineffective and Harmful in Cancer Treatment
Raw apricot kernels, while rich in flavonoids, antioxidants, and other nutrients, carry significant health risks due to the presence of amygdalin, a compound that releases toxic cyanide when ingested.
Health Risks
Apricot kernels contain amygdalin, which can lead to cyanide poisoning. Symptoms of excessive intake can be severe and potentially fatal [2][4]. To reduce the risk, preparation methods such as roasting or soaking are recommended, as they decrease amygdalin content [2]. However, even with proper preparation, a recommended daily intake of only 1-2 kernels is advised to avoid toxicity [2].
Potential Benefits
The anti-inflammatory and antioxidant properties of apricot kernels are attributed to their flavonoids and antioxidants. Research suggests an inverse relationship between apricot kernel flavonoids and asthmatic symptoms, indicating some respiratory and inflammation-related benefits [3]. Additionally, apricots and their parts are rich in antioxidants like carotenoids, beta-carotene, vitamin E, and other micronutrients that support general health [1][3][5].
However, these benefits are primarily attributed to the fruit rather than the raw kernels. The potential danger of cyanide toxicity generally outweighs these benefits unless consumption is carefully controlled and kernels are properly prepared.
Cautionary Advice
Given the serious risk of cyanide poisoning, it is advisable to avoid eating raw apricot kernels in unregulated or high quantities. Consultation with a healthcare professional is recommended before use for health purposes.
The possible health benefits of raw apricot kernels must be balanced carefully against the risk of cyanide poisoning [2][3][4].
Related Research
Cancer Research UK discusses laetrile (amygdalin or Vitamin B17), but states that it is not a proven treatment for cancer and may be harmful. The Cochrane Database of Systematic Reviews has not found any evidence to support the use of laetrile as a treatment for cancer. WebMD questions the safety of amygdalin as a cancer treatment, and Periodicum Biologorum has conducted a study on the effect of amygdalin on the treatment and recurrence of endometriosis in an experimental rat study, but found no significant results.
The European Food Safety Authority advises against consuming apricot kernels due to the risk of cyanide poisoning, and the Research and Development Institute for Bovine Balotesti does not discuss the use of laetrile as a treatment for cancer. NIH PubChem provides information on amygdalin, including its chemical structure and potential pharmacological activities, but does not support its use as a cancer treatment.
Research in Pharmaceutical Sciences has found anti-inflammatory effects of Prunus Armeniaca L. (Apricot) extracts on ulcerative colitis in rats, but not related to laetrile or amygdalin.
For more information on the history and current usage of amygdalin and laetrile, refer to the Marion Institute.